This website page has temporary specifics of bortezomib and a group of one-way links to more information about using this drug, research outcomes, and ongoing scientific trials.
Drug Formulary details is intended to be used by Health care gurus. It isn't intended to be healthcare guidance. A number of the information, like details about funding for cancer medication, will not use to all individuals.
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carbamazepine will reduce the extent or influence of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
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bortezomib improves levels of lomitapide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Lomitapide dose should not exceed thirty mg/working day.
cannabidiol will improve the level or impact of bortezomib by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Closely. Contemplate minimizing the dose of sensitive CYP2C19 substrates, as clinically correct, when coadministered with cannabidiol.
anastrozole will boost the degree or result of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.
Peripheral neuropathy: Facts exhibit that bortezomib can cause peripheral neuropathy when coupled with other prescription drugs like isoniazid, amiodarone, and Verteporfin HMG-CoA reductase inhibitors. So, close checking of neurological deficits is a robust recommendation.
explain to your doctor if you are Expecting or prepare to become Expecting. Bortezomib may hurt the fetus. Use beginning Regulate to forestall pregnancy through your remedy with bortezomib and for at least 7 months immediately after your closing dose. In case you are a Thalicarpine male which has a feminine partner who could come to be pregnant, you'll want to use delivery Manage during your cure with bortezomib and for at Atpenin A5 least 4 months after your ultimate dose.
Bortezomib is FDA-authorised for use while in the Original therapy of various myeloma in combination with cyclophosphamide and dexamethasone. Additionally it is FDA-approved for use while in the cure of several myeloma in people who Earlier responded to bortezomib and relapsed at least six months after the completion on the prior procedure.
verapamil will improve the amount or outcome of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Bortezomib may bring about Unintended effects. Explain to your medical professional if any of such signs or symptoms, or Individuals in the Exclusive PRECAUTIONS part, are serious or never go away: